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Inflammation is a key driver of all stages of oncogenic progression 47 , and given that cigarette smoke or E-liquid aerosol inhalation can promote inflammatory cytokine production 24 , we next explored whether BCEVs were capable of potentiating these oncogenic inflammatory responses

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In another embodiment of the invention, wherein all the three sections are linearly joined together in succession using a thin wall tube made of light material selected from the group consisting of thin wall plastic tube, paper, plastic wrapped paper and aluminum foil